"The Long Run" Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something ...
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Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer
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Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.Oleh Timmerman Report
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Ep167: Leslie Williams on transfer RNA therapies
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Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.Oleh Timmerman Report
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Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity
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Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.Oleh Timmerman Report
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Ep165: Zach Hornby on Tackling Cancer Drug Resistance
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Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.Oleh Timmerman Report
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Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients
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Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.Oleh Timmerman Report
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Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases
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Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.Oleh Timmerman Report
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Ep162: Sean McClain on AI for Biologic Drug Discovery
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Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.Oleh Timmerman Report
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Ep161: Jeff Stein on a Long-Lasting Flu Drug
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Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.Oleh Timmerman Report
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Ep160: Abe Ceesay on Precision Neuroscience
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Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.Oleh Timmerman Report
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Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease
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Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.Oleh Timmerman Report
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Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery
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David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.Oleh Timmerman Report
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Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery
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Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.Oleh Timmerman Report
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Ep156: David Liu on New Tools and Techniques for Biology
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David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.Oleh Timmerman Report
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Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's
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Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.Oleh Timmerman Report
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Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer
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Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.Oleh Timmerman Report
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Ep153: Rick Young on Studying Gene Expression for Drug Discovery
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Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.Oleh Timmerman Report
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Ep152: Jens Eckstein on Investing in Healthy Aging
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Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.Oleh Timmerman Report
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Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer
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Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.Oleh Timmerman Report
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Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance
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Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.Oleh Timmerman Report
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Ep149: Nancy Stagliano on Precision Neuroscience
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Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.Oleh Timmerman Report
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Ep148: Diana Brainard on the Fight Against Infectious Disease
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Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.Oleh Timmerman Report
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Ep147: Reid Huber on Investing in the Future of Medicine
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Reid Huber, partner at Third Rock Ventures, on investing in the future of medicine.Oleh Timmerman Report
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Ep146: Jeff Huber on Life in Tech and Biotech
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Jeff Huber, co-founder and general partner at Triatomic Capital, on his career path in tech, and then biotech.Oleh Timmerman Report
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Ep145: Lori Lyons-Williams on Targeted Radiopharmaceuticals for Cancer
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Lori Lyons-Williams, CEO of Abdera Therapeutics, on developing targeted radiopharmaceuticals for cancer.Oleh Timmerman Report
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Ep144: Turning the Tables, Rob Perez Interviews Me
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Turning the Tables, Rob Perez Interviews MeOleh Timmerman Report
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Ep143: Zach Weinberg and Alexis Borisy on Freeing the Biotech Founders
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Zach Weinberg and Alexis Borisy of Curie.Bio on Freeing the Biotech FoundersOleh Timmerman Report
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Ep142: Fred Appelbaum on how 'Living Medicine' Came to Be
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Fred Appelbaum, a physician, scientist and leader at the Fred Hutchinson Cancer Center, on 'Living Medicine,' his new book about the development of bone marrow transplantation and the rise of cell therapy.Oleh Timmerman Report
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Ep141: Colin Hill on Digging Deep into Data, Finding New Drug Targets
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Colin Hill, co-founder and CEO of Aitia, on digging deep into biological datasets and finding new drug targets.Oleh Timmerman Report
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Ep140: Yung Lie on Supporting Young Scientists with Bold, Brave Ideas
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Yung Lie, president and CEO of Damon Runyon Cancer Research Foundation, on advancing cancer research by supporting young scientists with bold and brave ideas.Oleh Timmerman Report
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Ep139: Kevin Conroy on Early Detection of Cancer
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Kevin Conroy, CEO of Exact Sciences, on early detection of cancer.Oleh Timmerman Report
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Ep138: Jodie Morrison on Becoming a Biotech CEO
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Jodie Morrison, acting CEO of Q32Bio, on becoming a biotech CEO.Oleh Timmerman Report
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Ep137: Aaron Ring on Immunotherapy for Cancer & More
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Aaron Ring, a scientist at Yale moving to the Fred Hutchinson Cancer Center, on applying immunology and protein engineering for cancer therapy and more.Oleh Timmerman Report
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Ep136: Deborah Palestrant on Building Biotech Startups
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Deborah Palestrant, partner at 5AM Ventures and head of the 4:59 initiative, on building biotech startups.Oleh Timmerman Report
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Ep135: John Maraganore on Developing a New Class of Medicines
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John Maraganore, former founding CEO of Alnylam Pharmaceuticals, on his life in biotech and developing RNA interference as a new class of medicine.Oleh Timmerman Report
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Ep134: Emile Nuwaysir on In Vivo Gene Editing Therapies
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Emile Nuwaysir, CEO of Boston-based Ensoma, on developing off-the-shelf in vivo gene editing therapies.Oleh Timmerman Report
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Ep133: Catherine Stehman-Breen on Epigenetic Editing Therapies
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Catherine Stehman-Breen, CEO of Boston-based Chroma Medicine, on developing epigenetic editing therapies.Oleh Timmerman Report
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Ep132: Eric Dobmeier on Treating Kidney Disease
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Eric Dobmeier, CEO of Seattle-based Chinook Therapeutics, on new strategies for treating kidney diseases.Oleh Timmerman Report
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Ep131: Ryan Watts on Neuroscience Drug R&D
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Ryan Watts, CEO of South San Francisco-based Denali Therapeutics, on neuroscience drug discovery and development.Oleh Timmerman Report
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Ep130: David Hallal on a Life in Biotech & the Cell Therapy Wave
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David Hallal, CEO of ElevateBio, on a long career in biotech and the coming 50-year opportunity in cell therapy and gene therapy.Oleh Timmerman Report
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Ep129: Joanne Smith-Farrell on Engineered B-Cell Therapies
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Joanne Smith-Farrell, CEO of Cambridge, Mass.-based Be Biopharma, on Engineered B-Cell Therapies for Cancer & Rare Diseases.Oleh Timmerman Report
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Ep128: Rick Berke on Building a Biotech Journalism Outlet to Last
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Rick Berke, co-founder and executive editor of STAT, on building a biotech journalism outlet to last.Oleh Timmerman Report
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Ep127: Jeb Keiper on Computational Drug Discovery
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Jeb Keiper, CEO of Nimbus Therapeutics, on computational drug discovery, an unusual business model, and an important new Tyk2 inhibitor for psoriasis and other forms of autoimmunity.Oleh Timmerman Report
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Ep126: DA Wallach on Becoming a Biotech VC
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DA Wallach, founder and general partner of TIME Bioventures, on becoming a biotech venture investor.Oleh Timmerman Report
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Ep125: Barry Greene on a New Drug for Depression
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Barry Greene, CEO of Cambridge, Mass.-based Sage Therapeutics, on plans to introduce a new type of treatment for depression and postpartum depression.Oleh Timmerman Report
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Ep124: Shehnaaz Suliman on Delivery of Genetic Medicines
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Shehnaaz Suliman, CEO of ReCode Therapeutics, on lipid nanoparticle delivery of genetic medicines.Oleh Timmerman Report
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Ep123: Tariq Kassum on Single-Cell Analysis for Drug Discovery
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Tariq Kassum, CEO of Cambridge, Mass.-based Celsius Therapeutics, on using single cell technology for drug discovery.Oleh Timmerman Report
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Ep122: Aetna Wun Trombley on Extracellular Protein Degraders
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Aetna Wun Trombley, CEO of Lycia Therapeutics, on extracellular protein degraders.Oleh Timmerman Report
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Ep121: Samantha Truex on Going Upstream Against Severe Asthma
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Samantha Truex, CEO of Upstream Bio, on a new approach to treating severe asthma and other inflammatory diseases.Oleh Timmerman Report
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Ep120: Tim Lu on Gene Circuits for Cell Therapy
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Tim Lu, CEO of Senti Biosciences, on developing gene circuits for cell therapy.Oleh Timmerman Report
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Ep119: Jo Viney on Discovering Treatments for Autoimmune Disease
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Jo Viney, CEO of Seismic Therapeutic, on discovering new treatments for autoimmune disease.Oleh Timmerman Report
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