Podcast Malaria terbaik (2025)

1
Insecticide-Treated Baby Wraps Cut Malaria Cases by Two-Thirds in Uganda 1:29

6d ago1:29

1:29

A new study in rural western Uganda finds that treating baby-carrying cloths, or lesu, with an insecticide with modest repellent effect significantly reduces malaria infections in young children. Transcript In many parts of sub-Saharan Africa, mothers carry their young children on their backs in colorful cotton wraps called lesu. Could treating the…

1
EXTENDED: Boosting Mosquito Immunity to Fight Malaria (with Emma Camacho) 7:38

17d ago7:38

7:38

Too much can kill the mosquito — too little can also kill it. But the right amount can strengthen the mosquito's defenses and stop malaria transmission. Today, the Goldilocks dose. Emma Camacho shares how a natural compound called L-DOPA strengthens mosquitoes' defenses at just the right concentration, revealing a new way to block malaria transmiss…

1
The tyranny of Defeat, Distraction and Dependency 17:03

2M ago17:03

17:03

Malaria elimination is still a distant dream in Africa. This episode discusses how we can get away from the tyranny of Defeat, Distraction and Dependency.Oleh Silas Majambere

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Understanding Artemisinin Resistance: A Deep Dive into Malaria's Complexity 19:03

2M ago19:03

19:03

Malaria, one of humanity's most enduring adversaries, continues to claim millions of lives, particularly among children. This episode delves into the complexities surrounding the effectiveness of Artemether Lumefantrine, commonly known as Cortum, which has long stood as the foremost treatment against malaria. Despite its historical success, recent …

1
Confronting Malaria: The Efficacy of Artemether-Lumefantrine Under Threat 21:54

2M ago21:54

21:54

Today, we engage in a profound examination of a formidable global health challenge: malaria. This disease, particularly driven by the Plasmodium falciparum parasite, remains a persistent adversary, especially within sub-Saharan Africa. Our primary focus is on Artemether-Lumefantrine, commonly known by its brand name, Cortem, which has served as a c…

1
The Goldilocks Dose: Modulating Mosquito Diet to Control Malaria 1:19

2M ago1:19

1:19

Feeding mosquitoes L-DOPA can either strengthen their defences against malaria or shorten their lifespan — showing that in vector control, the dose makes the difference Transcript As with all medicine, the dose determines whether something helps or harms. Researchers recently looked at a substance commonly found in mosquito habitats that might form…

1
SPECIAL: Hackathons for Malaria Genetic Epidemiology (with Bryan Greenhouse) 10:45

3M ago10:45

10:45

How do you turn vast amounts of genetic data into actionable insight – efficiently and accurately? Professor Bryan Greenhouse of UCSF discusses a series of "hackathons" at the Johns Hopkins Malaria Research Institute (JHMRI) that bring together scientists from around the world to tackle one of the biggest challenges in malaria research: analyzing p…

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EXTENDED: From River Blindness to Malaria Control – The Ivermectin Story (with Carlos Chaccour and Joseph Mwangangi) 11:33

3M ago11:33

11:33

In Kwale, Kenya, where bed nets alone can't stop malaria, researchers are testing ivermectin – a drug long used to treat parasitic infections – as a new way to kill mosquitoes. Trials show a 26% drop in malaria cases and added benefits against other mosquito-borne diseases, suggesting ivermectin could be a scalable, community-driven tool in the fig…

1
Ivermectin's Potential in the Fight Against Malaria 1:31

3M ago1:31

1:31

A new study in Kenya shows that mass drug administration of ivermectin safely reduced malaria cases by 26%, offering a promising supplement to insecticide-based prevention. Transcript Bed nets and insecticides are commonly used to prevent malaria transmission. But insecticide resistance is making those tools less effective. There's a growing intere…

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EXTENDED: The Turning Point – What Drives Malaria to Become Severe? (with Mark Travassos, Mahamadou Ali Thera and Rafal Sobota) 13:33

4M ago13:33

13:33

Focusing on patients in Mali, researchers examine why some children develop life-threatening complications like cerebral malaria or severe malarial anemia. With Mark Travassos (University of Maryland School of Medicine), Mahamadou Ali Thera (University of Science Techniques and Technologies of Bamako), and Rafal Sobota (Northwestern University). Ab…

1
What Severe Malaria Cases Have In Common 1:27

4M ago1:27

1:27

Although severe malaria presents in different clinical forms – such as cerebral malaria or severe malarial anemia – a new study reveals that all severe cases have one thing in common: a shared inflammatory signature Transcript Whilst most cases of malaria are mild, some take a dangerous turn. In severe cases, the malaria parasite can overwhelm the …

1
EXTENDED: Curing the Mosquito – Bed Nets That Target Parasites (with Alexandra Probst) 8:13

5M ago8:13

8:13

Dr. Alexandra Probst discusses a breakthrough in malaria prevention: bed nets coated with anti-parasitic drugs that stop transmission by curing infected mosquitoes. With Alexandra Probst, former graduate student at Harvard University. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to h…

1
Bed Nets That Target Parasites, Not Just Mosquitoes 1:16

5M ago1:16

1:16

How next-generation bed nets could stop malaria by killing the parasites inside mosquitoes, not just the mosquitoes themselves. Transcript Bed nets have long been a cornerstone of vector control. Coated with insecticide, they serve a dual purpose: preventing bites and killing mosquitoes. But what if those nets could do more – not only kill the mosq…

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EXTENDED: Why Malaria Vaccines May Work Better in Some Places Than Others (with Lemu Golassa) 5:19

6M ago5:19

5:19

The extent to which malaria vaccines reduce cases and deaths is a key consideration. But there's another factor, too. with Dr. Lemu Golassa, Head of Medical Parasitology at Addis Ababa University. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research an…

1
Mismatch Between Malaria Vaccines and Local Parasite Strains in Ethiopia 1:33

6M ago1:33

1:33

A recent study in Ethiopia reveals that local malaria parasite strains differ genetically from those targeted by current vaccines, potentially reducing their effectiveness. Transcript The recent introduction of two malaria vaccines in sub-Saharan Africa represents a major success in global health, and the culmination of decades of research and deve…

1
#14 PAMCA Crisis Part 2 1:05:58

6M ago1:05:58

1:05:58

This is part 2 of a two-part series dedicated exclusively to The Pan-African Mosquito Control Association – PAMCA. We discuss the issues around the legality of the current board, and the rumors of financial mismanagement inside PAMCA.Oleh Silas Majambere

1
Malaria Advocacy on Capitol Hill: Funding, Research, and Global Impact 15:53

7M ago15:53

15:53

The podcast explores the importance of advocacy for malaria research and control. It follows over 120 advocates gathering in Washington, DC, as part of the 'United to Beat Malaria' campaign, urging Congress to continue supporting global malaria efforts. Key topics include: The US President's Malaria Initiative (PMI), founded in 2005, which provides…

1
EXTENDED: AI-Driven Malaria Control – Neural Networks and the Task-Shifting of Vector Surveillance (with Soumya Acharya and Sunny Patel) 12:48

7M ago12:48

12:48

With a shortage of entomologists in malaria-endemic regions, could AI fill the gap? We explore VectorCam, an offline tool powered by a Convolutional Neural Network that aims to support local vector surveillance. with Dr. Soumya Acharya and Sunny Patel of Johns Hopkins University. About The Podcast The Johns Hopkins Malaria Minute is produced by the…

1
#13 PAMCA Crisis Part 1 1:02:59

7M ago1:02:59

1:02:59

The Pan-African Mosquito Control Association (PAMCA) has been going through a leadership and management crisis for 2 years now. In this first part of a two-part series, I have invited four guests, who have worked for PAMCA for several years, to discuss how PAMCA was organized and what brought it to the current stalemate.…

1
VectorCAM: The AI Tool Improving Mosquito Detection 1:22

7M ago1:22

1:22

Can AI identify mosquito species? VectorCAM, a pocket-sized device, uses machine learning to differentiate species with 95% accuracy, enhancing malaria surveillance efforts Transcript Not all mosquitoes are created equal. Of the more than three thousand species, only a limited number of the Anopheles genus can transmit malaria. Even within that sub…

1
EXTENDED: Could a Juice Pouch Revolutionize Mosquito Control? (with George Dimopoulos) 9:21

8M ago9:21

9:21

For decades, insecticides have shielded us from malaria—but cracks are showing. Resistance is spreading, and environmental concerns are growing. Could a simple pouch of fruit juice with a powerful secret be the breakthrough we need? with George Dimopoulos of the Johns Hopkins Malaria Research Institute About The Podcast The Johns Hopkins Malaria Mi…

1
Fighting Malaria with Soil Bacteria 1:16

8M ago1:16

1:16

One of the main ways of controlling malaria is to reduce mosquito populations through insecticides. But the mosquitoes are developing resistance, making most insecticides less effective. What if the answer lies beneath our feet? Transcript One of the main ways of controlling malaria is to reduce mosquito populations through insecticides. But the mo…

1
EXTENDED: Mapping Social Networks to Strengthen Malaria Prevention (with András Vörös and Elisa Bellotti) 12:13

9M ago12:13

12:13

The prevention of malaria depends upon multiple layers of interventions that work together to reduce cases and deaths. But what makes someone decide to sleep under a bed net, or apply an insecticidal cream? What makes one person take up more interventions than another? How influential are government-accredited health experts versus friends and fami…

1
How Conversations Shape Malaria Prevention Practices 1:25

9M ago1:25

1:25

Malaria prevention depends on the adoption of multiple behaviors – like sleeping under a bednet and wearing clothes that cover the skin. Researchers find that conversations with people in one's own social circle are the strongest factors that influence behavior uptake. Transcript Malaria prevention depends on the adoption of multiple behaviors – li…

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EXTENDED: Discovering New Targets for Malaria Vaccines and Monoclonal Antibodies (with Joshua Tan) 8:47

10M ago8:47

8:47

Today, the discovery of antibodies targeting a new region of the malaria parasite that could serve as a promising target for drugs and vaccines.

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Scientists Uncover 'Site of Vulnerability' in Malaria Parasites 1:29

10M ago1:29

1:29

Scientists discover new antibodies - a promising target for clinical exploration. Transcript The currently licenced malaria vaccines and monoclonal antibodies all target a well-known region of the same malaria protein. That protein – the circumsporozoite protein, commonly known as CSP – covers the surface of the parasite as it enters the human skin…

1
EXTENDED: How AI Chatbots Could Help Predict Antimalarial Drug Resistance Before It Strikes (with Robert Opoka and Elizabeth Winzeler) 12:31

11M ago12:31

12:31

We focus on drug resistance and the troubling news that the frontline drug against malaria, artemisinin, is failing due to resistant parasites in severe cases of malaria, and how the collective efforts of drug development – and the data produced – could be used to build an AI chatbot capable of predicting resistance before it strikes. With Robert O…

1
How to Predict (And Avert) Antimalarial Drug Resistance 1:16

11M ago1:16

1:16

Researchers search for ways to predict antimalarial drug resistance and identify more effective drug combinations. Transcript The front-line treatment for malaria is typically a combination of drugs called artemisinin-based combination therapy. Resistance to treatment has already been reported in mild cases of malaria, but now, for the first time, …

1
'Big Push' Needed to Turn Tide on Malaria – WHO 1:23

11M ago1:23

1:23

The World Health Organization has today released its annual World Malaria Report. Here are the takeaways. Transcript The World Health Organization has today released its annual World Malaria Report. Here are the takeaways. Since the turn of the century, the global malaria community has averted over 2.2 billion malaria cases and 12.7 million deaths,…

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EXTENDED: Listening to Malaria – How Lasers and Ultrasound Could Revolutionize Diagnosis (with Sunil Parikh, Vladimir Zharov and Yap Boum) 11:43

12M ago11:43

11:43

An innovative, non-invasive diagnostic tool that could revolutionize malaria testing, with the potential to be built into wearable devices. In this extended episode of the Johns Hopkins Malaria Minute, we ask: What are the limitations of current malaria diagnostic methods? How is a 'cytophone' - and what makes it innovative? Why is the detection of…

1
The Skin-Contact Malaria Test That Could Revolutionize Diagnostics 1:10

1y ago1:10

1:10

Using lasers and ultrasound, the 'cytophone' detects a key byproduct of all malaria parasites. Transcript Among the most commonly used malaria diagnostic tests is the rapid diagnostic test (RDT), which detects malaria antigens from a drop of blood. Whilst RDTs are small and cheap, they're invasive and new strains of the parasite have evolved that c…

1
#12 Where Is Hope? 7:00

1y ago7:00

7:00

There are many reasons to lose hope. But you can choose to remain hopeful. Here are my reasons.Oleh Silas Majambere

1
EXTENDED: First Reference Genome Sequence of P. vivax from Ethiopia (with Jane Carlton, Delenasaw Yewhalaw, and Francisco Callejas Hernandez) 8:59

1y ago8:59

8:59

Today, how DNA from a single patient in Ethiopia can shed light on the big picture of malaria. Why is Plasmodium vivax significant in malaria research, especially in Ethiopia? How does genomic sequencing contribute to understanding and controlling malaria? How are advances in sequencing technology influencing malaria research? With Jane Carlton, De…

1
How Comparative Genomics Can Help Find the Best Treatments for Malaria 1:13

1y ago1:13

1:13

'Comparative genomics' helps identify genes that can serve as targets for future drugs and vaccines. Transcript Not all parasites are alike. Genetic mutations mean that malaria parasites evolve differently in different regions – and even within the same region. One species thought to be particularly genetically diverse is Plasmodium vivax. It's the…

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EXTENDED: The Surprising Advantage of Transmission-Blocking Vaccines (with Ilinca Ciubotariu, Qixin He and Giovanna Carpi) 9:22

1y ago9:22

9:22

The World Health Organisation has recommended two licenced malaria vaccines. Those vaccines have been a long time coming - but are they the best? In this extended episode of the Johns Hopkins Malaria Minute, we ask: Why is developing a malaria vaccine so challenging? How does antigen variation play affect the effectiveness of malaria vaccines? What…

1
Transmission-Blocking Antigens Show Low Variation, Making Them a Reliable Vaccine Target Across Countries 1:14

1y ago1:14

1:14

A key challenge in developing a malaria vaccine is choosing which stage to target. Transcript A key challenge in developing a malaria vaccine is choosing which stage of the infection to target. You can target the parasite when it enters the body, multiplies in the liver and the blood, or is in the sexual stage, preparing to be picked up by a mosqui…

1
EXTENDED: World Mosquito Day - Gene Drives and CRISPR Technology 13:19

1y ago13:19

13:19

We share a special episode of our podcast to mark World Mosqutio Day. World Mosquito Day, observed annually on August 20th, commemorates British doctor Sir Ronald Ross's discovery in 1897 that female Anopheles mosquitoes transmit malaria to humans. More than a century later, major advancements like genetically modifying mosquitoes—AKA gene drives—h…

1
Gene Drives: A Sharper Tool for the Malaria Toolkit? 1:15

1+ y ago1:15

1:15

People often talk about the 'malaria toolkit' - how might gene drives fit? Transcript When people talk about malaria, they often mention the 'malaria toolkit' – a set of tools, like bed nets and indoor residual spraying, that are available to help curb the spread of disease. In the past, these tools were trusty go-to's – thanks to their efficacy, s…

1
EXTENDED: CRISPR and Consent (Gene Drives Part I - with Anthony James and John Connolly) 12:24

1+ y ago12:24

12:24

Gene drives are a novel way of genetically editing the mosquitoes that transmit malaria. They have the potential to dramatically reduce cases and deaths. But the technology they're based on is new and requires new thinking on regulation. In this first episode of our two-part focus on gene drives, we ask how drives work – examining the CRISPR techno…

1
How Can We Tell Gene Drives Work? 1:19

1+ y ago1:19

1:19

Gene drives are a promising tool for malaria control - how can we tell they actually work? Transcript Gene drives are a promising new tool for malaria control. They involve releasing genetically modified mosquitoes into the wild – mosquitoes engineered to halt the parasites from developing inside the insects, or that cause the mosquitoes to die. Th…

1
EXTENDED: How Climate Change Could Lead To Faster, More Intense Malaria Transmission (with Alex Eapen) 7:07

1+ y ago7:07

7:07

Temperature, rainfall, and humidity determine malaria transmission - but climate change is altering each one of those variables. What might this mean for cases of the disease? With Alex Eapen, from the ICMR (Indian Council of Medical Research) in Chennai, India. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Mal…

1
Increase in Temperature Associated With Decrease in Incubation Period 1:21

1+ y ago1:21

1:21

Researchers compare the temperature of mosquito breeding spots with a decade early to examine its impact on malaria transmission. Transcript The effects of climate change on malaria are becoming clearer. Anopheles stephensi – an urban form of the malaria mosquito – is changing its geography, moving from Southeast Asia to parts of Africa and India. …

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EXTENDED: Investigating PfHDAC1 – The Essential Malaria Protein Behind Human Sickness (with Abhishek Kanyal and Krishanpal Karmodiya) 11:04

1+ y ago11:04

11:04

A single protein helps malaria parasites develop in the blood and cause disease symptoms. Could inhibiting this essential protein help curb the spread of disease? With Abhishek Kanyal and Krishanpal Karmodiya. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malari…

1
Blood-Stage Protein Identified as Key Target for Antimalarial Drugs 1:16

1+ y ago1:16

1:16

A poorly studied malaria protein could serve as a key drug target to help combat the growing problem of resistance. Transcript A poorly studied malaria protein – Plasmodium falciparum histone deacetylase 1 – could serve as a key drug target to help combat the growing problem of resistance. The protein helps regulate the 'intraerythrocytic' stage of…

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#11 A conversation with Dr Fitsum Tadesse, Lead Scientist at AHRI in Ethiopia 59:57

1+ y ago59:57

59:57

Dr Fitsum Tadesse is a Lead Scientist at the Armauer Hansen Research Institute (AHRI) in Ethiopia, a Wellcome Trust Fellow at LSHTM and an Alan J. Magill Fellow at ASTMH His work mainly focuses on the transmission of malaria parasites from humans to mosquitoes. His group recently demonstrated the contribution of the invasive mosquito, Anopheles ste…

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EXTENDED: What Sickle Cell Disease Reveals About Malaria and Human Evolution 8:32

1+ y ago8:32

8:32

How sickle cell disease can be a blessing and a curse. And why we need equity in genomic research and to diversify the genomes we sequence. With Ambroise Wonkam (Johns Hopkins University). About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to sha…

1
The Malaria Legacy of Sickle Cell Disease 1:18

1+ y ago1:18

1:18

Malaria is one of humanity's oldest diseases – and one with which we have evolved. Transcript Malaria is one of humanity's oldest diseases – and one with which we have evolved. Over time, it's put selective pressure on our genome to respond better to its infection. Sickle cell disease is one example. It causes a defect in hemoglobin – transforming …

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#10 A Conversation with Dr Anne Gasasira, Senior Programme Officer at the African Leaders Malaria Alliance 1:09:05

1+ y ago1:09:05

1:09:05

Dr Anne Gasasira is a Ugandan trained medical doctor and epidemiologist. She started her career in malaria and HIV research in the early 2000s. She worked on a research collaboration between Makerere University- University of California San Francisco on antimalarial drug efficacy and HIV–Malaria interaction studies. Since 2015, has been working wit…

1
EXTENDED: From Lab to Legislature – Meet the Scientists Taking on Capitol Hill in the Fight Against Malaria 12:04

1+ y ago12:04

12:04

On the steps of Capitol Hill, we meet the scientists bringing their scientific battle against malaria into the world of political advocacy. They join a 100+ group of advocates lobbying their members of Congress to fund critical interventions against malaria – becoming 'malaria champions' as well. We ask: Why have they decided to join the world of p…

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Advocacy on Capitol Hill: Uniting Scientific Research and Policy in the Fight Against Malaria 1:17

1+ y ago1:17

1:17

Malaria champions from 43 states gather in Washington D.C. to lobby their members of Congress about malaria. Transcript The malaria community is diverse. Some work on the parasites, others the mosquito. Others still focus on public health. The battle is being waged on the bench and the field. But there's another community fighting the disease on a …

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Malaria Podcast

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