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Episode #35: The Story of Ubiquitin with Dr. Aaron Ciechanover

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Konten disediakan oleh Mishka Narasimhan and Will Leidig, Mishka Narasimhan, and Will Leidig. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Mishka Narasimhan and Will Leidig, Mishka Narasimhan, and Will Leidig atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.

In this episode, Will sat down with Dr. Aaron Ciechanover, biologist and Distinguished Research Professor in the Rappaport Faculty of Medicine at the Technion, Israel Institute of Technology. Dr. Ciechanover is renowned for his work in studying the method that cells use to degrade and recycle proteins. While in the laboratory of Avram Hershko, they discovered that small proteins, called ubiquitin, were attached in chains to targeted proteins, marking them for degradation by a proteasome. This system is highly regulated and was subsequently found to be a factor in many diseases and areas of biology, so much that in 2004, Dr. Ciechanover was awarded the Nobel Prize in Chemistry while on faculty at Washington University. Enjoy!

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37 episode

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iconBagikan
 
Manage episode 423583169 series 3263421
Konten disediakan oleh Mishka Narasimhan and Will Leidig, Mishka Narasimhan, and Will Leidig. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Mishka Narasimhan and Will Leidig, Mishka Narasimhan, and Will Leidig atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.

In this episode, Will sat down with Dr. Aaron Ciechanover, biologist and Distinguished Research Professor in the Rappaport Faculty of Medicine at the Technion, Israel Institute of Technology. Dr. Ciechanover is renowned for his work in studying the method that cells use to degrade and recycle proteins. While in the laboratory of Avram Hershko, they discovered that small proteins, called ubiquitin, were attached in chains to targeted proteins, marking them for degradation by a proteasome. This system is highly regulated and was subsequently found to be a factor in many diseases and areas of biology, so much that in 2004, Dr. Ciechanover was awarded the Nobel Prize in Chemistry while on faculty at Washington University. Enjoy!

  continue reading

37 episode

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