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Episode 19. Management of Primary Myelofibrosis
Manage episode 360145933 series 3369804
Konten disediakan oleh Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Rajshekhar Chakraborty and Ashwin Kishtagari, Rajshekhar Chakraborty, Ashwin Kishtagari, and Edward Cliff atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.
In this episode, we discuss the diagnosis and management of primary myelofibrosis with Dr. Ayalew Tefferi at Mayo Clinic, Rochester, Minnesota. Here are the show notes, including key studies discussed in this episode:
1. Risk stratification of PMF:
MIPSS70 Score: http://www.mipss70score.it
https://ascopubs.org/doi/full/10.1200/JCO.2017.76.4886
Genetically inspired prognostic scoring system (GIPSS):
https://www.nature.com/articles/s41375-018-0107-z
Type 1 CALR mutation:
https://ashpublications.org/blood/article/124/15/2465/33454
MYSEC-PM:
http://www.mysec-pm.eu
https://www.nature.com/articles/leu2017169
2. Treatment of PMF with JAK inhibitors
https://pubmed.ncbi.nlm.nih.gov/36680511/
Momelotinib:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)02036-0/fulltext
Pacritinib : https://ashpublications.org/blood/article/140/Supplement%201/1518/490663
https://jamanetwork.com/journals/jamaoncology/fullarticle/2674384
Fedratinib:
https://onlinelibrary.wiley.com/doi/10.1111/bjh.18284
3. Allogeneic Transplant in PMF
https://ashpublications.org/hematology/article/2021/1/453/482995
Black African-American patients with primary myelofibrosis
https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2022009611/494460
4. Imtelestat in PMF
https://www.nejm.org/doi/full/10.1056/NEJMoa1310523
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