Bloody Minded podcast

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The Agile Brand with Greg Kihlström®

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#651: AI and in-house creative teams with Jen Rapp, Superside 29:27

7 hari yang lalu29:27

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29:27

With AI’s ability to augment in-house creative teams, how does that change the way organizations should approach both their creative strategies and how they evaluate the value of creative as a business function? Today, we’re joined by Jen Rapp, Chief Marketing Officer at Superside. Jen has had key roles at iconic brands like Patagonia, Arc’teryx, DoorDash, Owlet Baby, and Klaviyo. Now, she’s leading Superside’s rebrand with a focus on AI-powered creative services that augment in-house teams. RESOURCES Superside website: https://www.superside.com Wix Studio is the ultimate web platform for creative, fast-paced teams at agencies and enterprises—with smart design tools, flexible dev capabilities, full-stack business solutions, multi-site management, advanced AI and fully managed infrastructure. https://www.wix.com/studio Don't miss Medallia Experience 2025, March 24-26 in Las Vegas: Registration is now available: https://cvent.me/AmO1k0 Use code MEDEXP25 for $200 off registration Don't Miss MAICON 2025, October 14-16 in Cleveland - the event bringing together the brights minds and leading voices in AI. Use Code AGILE150 for $150 off registration. Go here to register: https://bit.ly/agile150 Connect with Greg on LinkedIn: https://www.linkedin.com/in/gregkihlstrom Don't miss a thing: get the latest episodes, sign up for our newsletter and more: https://www.theagilebrand.show Check out The Agile Brand Guide website with articles, insights, and Martechipedia, the wiki for marketing technology: https://www.agilebrandguide.com The Agile Brand podcast is brought to you by TEKsystems. Learn more here: https://www.teksystems.com/versionnextnow The Agile Brand is produced by Missing Link—a Latina-owned strategy-driven, creatively fueled production co-op. From ideation to creation, they craft human connections through intelligent, engaging and informative content. https://www.missinglink.company…

Bloody Minded

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Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.
Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

39 episode

#Science #Fitness #Biology #Podcasting Education #Medicine #Bloody Minded Crew #Haematology #Hematology #FOAM #Meded #Med School #Blood #Coagulation #Lymphoma

Bloody Minded

updated 5 hari yang lalu

Beranda serial•Feed

39 episode

#Science #Fitness #Biology #Podcasting Education #Medicine #Bloody Minded Crew #Haematology #Hematology #FOAM #Meded #Med School #Blood #Coagulation #Lymphoma

Semua episode

Bloody Minded

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Episode 38 - Infinity Products | Massive Transfusion Protocols 37:59

5 hari yang lalu37:59

37:59

Perfectly balanced, as all things should be. All that blood doesn’t just arrive when you snap your fingers together. The REALITY is you need the TIME and SPACE to thaw that frozen plasma and the strength of MIND to keep all the components in the right ratios. Only the chosen few with the POWER of transfusion medicine and the SOUL of the laboratory can direct the most immense of transfusions - the massive transfusion. Listen to this episode and maybe you can run the GAUNTLET of the MTP. Timestamps: 0:53 - Get ready for MASSIVE. TRANSFUSION. PROTOCOL. 1:45 - What is an MTP? 4:10 - A bleedy example 7:11 - Activating the MTP 8:52 - Consent in MTPs 11:16 - MTP packs 12:27 - Crossing plasma groups 15:30 - 1:1:1 Transfusion 17:29 - Whole Blood Transfusion 19:49 - Acidosis 22:21 - Hypothermia 23:14 - Hypocalcaemia 25:12 - Resus Associated Coagulopathy 25:49 - DIC 26:58 - Trauma Induced Coagulopathy 29:19 - Summary of Resuscitative Endpoints 31:05 - Viscoelastic testing 33:12 - Factor Concentrates 34:55 - Take home messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 37 - Red Cell Matchmaking | Group and Hold, Antibody Screen, Crossmatch 32:56

12 hari yang lalu32:56

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It’s an early trip to the lab this season to explore exactly how we safely match the blood in the bank to the patient on the ward. Follow your trusty hand-labelled group-and-hold tube as we unpack what actually goes into blood grouping, antibody screening and the final hurdle, the crossmatch! Timestamps 0:52 - Nick lives in squalor, surprising nobody 2:56 - The Group 4:22 - The Forward Group 6:53 - The Reverse Group 10:55 - The Antibody Screen 18:12 - DAT vs IAT 20:39 - The Crossmatch 25:08 - Anamnestic Antibody Responses 27:58 - Phenotyping 30:25 - Episode Summary Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 36 - What’s in the bag, Somerset, what’s in the bag? | Blood Products 40:28

19 hari yang lalu40:28

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We’re back again to answer all of your questions- what’s exactly is a "unit" of blood and how do we go about giving it? What on earth is the difference between FFP and ELP and cryodepleted plasma? And what do each of them sound like, if you were to interpret them via a completely unnecessary collection of household objects? As always, we’ve got you covered. Timestamps: 00:55 - Bashar's special presentation 03:42 - Where do we get blood from? 05:53 - Packed Red Blood Cells (PRBC) 08:20 - When and how to transfuse PRBC 11:07 - Clerical checks 13:02 - Platelets 18:12 - Plasma products 18:32 - Fresh Frozen Plasma (FFP) 20:00 - FFP vs ELP 24:00 - Cryodepleted plasma 25:10 - Cryoprecipitate 27:24 - Albumin 28:15 - Fractionated clotting factors 29:07 - Immunoglobulins 31:12 - Leukocyte tranfusion 34:57 - Reducing transfusion-transmitted infection 38:00 - Take home messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 35 - The Other Resus | Introduction to Blood Groups 49:57

26 hari yang lalu49:57

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We’ve been out of line with the rest of #FOAM #MedEd podcasts for the longest time. Forget that haematology stuff, it’s time to talk about RESUS. Break out your adrenaline, it’s time to crack some chests and… wait what? You meant Rhesus ? With an H? Oh right… okay. Put down those trauma shears as the only thing we’ll be cracking open are the ISBT Red Cell Immunogenetics guidelines. Join the Bloody Minded Crew take you though the basics of blood grouping with a focus on ABO and Rhesus. Timestamps: 0:56 - Cale needs help with the target 3:00 - Intro to blood groups 6:02 - What is a "blood group?" 8:40 - Historical diversion on blood groups! 9:47 - Cale speaks flawless German 13:49 - The ABO group: the hatted and the hatless 18:12 - The Bombay phenotype! No hat, no hair. 20:38 - ABO frequencies 21:11 - ABO compatibilities 21:49 - Interesting (to us) ABO tidbits 24:43 - Intro to Rhesus 29:13 - Nomenclature - RhD, C, c, E, e 36:27 - Wiener classification (brace yourself) 46:27 - Take home messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 34 - On the Wards: I would do anything for blood – but I won’t do that | Transfusion Reactions 1:02:08

7 weeks yang lalu1:02:08

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Do you fear – The Power of Blood? Have you been warned – You can’t Hurry Blood? Today we tackle all the ways Blood (and love) can go wrong. . . and how to manage it on the wards. Too cryptic? Join Bloody Minded's own consultant haematologist Dr Alison Chandler and the rest of the Bloody Minded Crew as we cover the many and varied reactions patients can have when you try and fix that haemoglobin level on the ward. Timestamps 00:53 - 3-4 nerds chatting about nonsense 03:37 - Your first transfusion reaction 05:08 - What is a transfusion reaction? 5:52 - Categorising transfusion reactions 7:26 - Acute febrile reactions 17:20 - Summary of acute febrile reactions 17:45 - Acute non-febrile transfusion reactions 22:11 - Workup and management of an acute reaction 37:44 - Delayed febrile reactions 50:08 - Delayed non-febrile reactions 53:46 - Summaries Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 33 - CAR-T and Chromothripsis | Multiple Myeloma Review with Dr Christian Bryant 1:02:02

9 weeks yang lalu1:02:02

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Myeloma beware, it's time to bring out the big guns. We are incredibly thankful to be joined by a peak predator of plasma cells, Dr. Christian Bryant. He is a consultant Haematologist at RPA in Sydney, has a PhD on the immunology of myeloma and is driven by a passion to improve the treatment and understanding of all things myeloma. TIMESTAMPS 2:18 - Intro to Christian Bryant 3:05 - Why Haematology? 5:31 - Why (oh god why) myeloma? 7:28 - Heavy metal, heavy chains 9:28 - Chromothripsis - The Cause That Breaks The Camel's Back? 13:45 - In praise of plasma cells 18:38 - Genomics to risk-stratify precursor states - should we bother? 20:32 - Predicting response and high risk disease 21:43 - IMS Criteria - High Genomic Risk 28:22 - Response Kinetics - When are you nervous? 31:31 - Balancing maintenance Len vs. secondary malignancies 39:34 - Other agents for maintenance? 44:44 - CAR-T - A New Hope? 49:10 - T cell exhaustion 50:21 - What are the CAR-T target molecules for MM? 53:27 - Any hope for a cure? 57:35 - MRD Matters Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 32 - Phagocytose. Pray. Love. | Haemophagocytic Lymphohistiocytosis (HLH) 41:19

10 weeks yang lalu41:19

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Ferritin keeps climbing and you’re getting jumpy? Did you consult Haem and then they were bedside 5 minutes later? Ever had to donate your own blood to test the patient for something? Join Nick, Cale and Bashar as we unpack a very special bonus episode on another deadly TLA, HLH. TIMESTAMPS 3:24 - History of HLH 5:26 - What is a histiocyte? 7:44 - How do you turn *off* an immune response? 8:52 - HLH - A Definition 10:49 - What are NK cells? 13:03 - Primary HLH - "HLH Disease" 13:34 - Secondary HLH - "HLH Syndrome" 14:46 - Causes of familial HLH 16:34 - Infective causes 18:05 - Malignant causes 20:24 - Clinical presentation and diagnostic criteria 32:47 - H-Score 34:36 - Treatment - Replacing Your Dodgy Off Switch 38:04 - Prognosis 38:55 - Take Home Messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 31 - Advanced Myeloma Nursing with A/Prof Tracy King 54:25

11 weeks yang lalu54:25

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Thankfully, it's time for an actual expert to join us again on Bloody Minded! We are thrilled to be sitting down and chatting with A/Prof. Tracy King , Myeloma CNC from RPA Hospital in Sydney, Co-Founder and past president of the HSANZ Nursing Group. From convenient treatment schedulers to the side effects we should be thinking more about to many ideas to improve clinical practice, this is a veritable hour of power worth diving into. TIMESTAMPS 2:23 - Intro to Tracy King 3:30 - A Nightingale Sang in Hammersmith Square 5:22 - How did you get into myeloma nursing? 9:35 - If not nursing, what? 10:50 - What is a CNC? 14:12 - Nursing expertise in myeloma - best supportive care 16:57 - The most asked questions 19:54 - Strategies to manage complex regimens 23:13 - MyeTxScheduler - A Godsend 26:37 - What do we miss, what should we be asking more? 28:21 - The crux of communication issues 29:33 - "What matters to you today" 29:49 - Patient advocacy groups 32:04 - Steroid side effects - there's just so much dex... 35:37 - M protein variations - how to see the forest for the trees 38:22 - Time toxicity 45:44 - Quality of life assessment tools 49:35 - How to get started in advocacy/education/further work? 51:57 - Organisations - find your tribe Also we promised to link MyeTx here so have at it https://rego.interact.technology/myetx/#/main Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 30 - Schnitzler’s List | Other Paraprotein Associated Diagnoses 36:18

12 weeks yang lalu36:18

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All that glitters isn’t gold, and all that paraproteins isn’t myeloma. But if we’re not going to blame myeloma, then what else might be responsible? Hold on to your M-Spikes as we the Bloody Minded Team dive into the weird and wonderful world of paraproteins causing havoc in patients without myeloma. This episode isn’t for the faint of blood so get ready for an advanced look at paraproteins and take a bit of the U out of MGUS. 2:12 - The Problem with "Unknown" Significance 8:45 - Waldenström's macroglobulinemia/Lymphoplasmacytic Lymphoma 11:17 - Marginal zone lymphoma 12:42 - Cold Agglutinin Disease 15:09 - Heavy chain disease 16:27 - POEMS Syndrome 23:10 - Other Paraproteinemic Neuropathies 25:55 - TEMPI 27:03 - CANOMAD 29:16 - Schnitzler Syndrome 31:34 - Scleromyxedema 34:06 - The “paraprotein AND...” approach Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 29 - On The Wards: It's Getting Hot in Here | Febrile Neutropenia 54:13

13 weeks yang lalu54:13

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Its time to hit the hot girl summer of haematology (we're in Australia after all) but also the hot boy winter and Autumn and Spring. Because our patients are hot all year round and sadly all night shift and possibly all throughout your ward round. Welcome to our next On The Wards episode looking at fevers in the haematology patient with a focus on the management of febrile neutropenia. There's a lot to cover in this jumbo sized episode and we're super happy that Dr Alison Chandler agreed to return after last time. Timestamps 2:08 - Episode Overview 4:47 - What is Febrile Neutropenia? 8:59 - Reminder: What are neutrophils 13:08 - Where did the neutrophils go? 18:24 - Why is FN a big deal? 20:00 - Assessing the neutropenic patient 30:15 - Antibiotics: Get them in 33:29 - Bugs: What grows? 36:15 - That fever isn't going away 41:01 - After the fever 42:24 - Can we make the neutrophils go up? 48:00 - Prophylaxis 52:50 - Summary Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 28 - In the Lab: Flow Cytometry, Mass Spectrometry & Cytogenetics in MM 42:26

14 weeks yang lalu42:26

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Can’t get enough of obscure haematological lab chat, can you? Well we’ve got good news for you! Join us today as we delve even deeper into the arcane depths of flow cytometry, mass spectrometry and cytogenetics as they apply to myeloma. We promise we didn’t just make these words up. 02:23 - Flow cytometry: overview 04:01 - The flow cytometer: practical aspects 09:01 - How we interpret flow 11:44 - Myeloma flow markers 14:32 - Quality in flow 21:26 - Mass spectrometry 25:59 - Cytogenetics 27:46 - Cytogenetics assay principles 30:30 - Karyotype abnormalities 31:44 - FISH and SNP arrays 33:05 - Cytogenetics and prognostication in MM 39:59 - Take home points Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 27 - In The Lab: Electrophoresis, Immunoelectrophoresis and Serum Free Light Chain Assays 48:14

15 weeks yang lalu48:14

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Thought you were free of myeloma acronyms? Don’t be ridiculous - this is the haematology lab! We were born in the acronyms, moulded by them. We didn’t see a complete word until advanced training and even then it was nothing but BLINDING. Your lab tests betray you because they belong to us… but in this episode we’ll let you in on some secrets. Join Nick, Cale and Bashar in the haematology (and closely adjacent immunology) lab as they chat about just how we do that electrophoresis, why an iEPG is different to an EPG and just how useful Bence-Jones proteins are(n’t). Timestamps 3:15 - Bone marrows - not as bad as they sound? 4:25 - What even do we do with the marrow? 10:57 - Eponymous plasma cells with weird morphology 13:04 - EPG - Electrophoresis 22:23 - IEPG - Immunoelectrophoresis 29:09 - What's the deal with Bence Jones proteins 33:27 - SFLC Measurements 37:07 - The Hook/Prozone Effect 40:55 - Light chain measurement in renal dysfunction 44:32 - Take Home Messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 26 - Trip to the Congo | Amyloidosis Overview 35:14

16 weeks yang lalu35:14

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MGUS and Myeloma too simple for your tastes? Do you like vague presentations and biopsying many tissues in a sometimes wild goose chase? Why does Congo have all the birefringent apples? Go ' AA aah ' as we TTR y to unpack AL l the problems that come with that most protean of disease - Systemic Amyloidosis! Timestamps 3:04 - Pathophysiology of Amyloid 6:52 - All The Subtypes of Amyloid 7:56 - AA Amyloid 10:08 - ABeta2M Amyloid 11:04 - Age-Related Amyloidosis = wtATTR = WTTA = SSA 14:38 - AL Amyloidosis 16:24 - Diagnosis of Amyloid 22:25 - Clinical Presentation of Amyloid 27:10 - Prognosis 32:17 - Take Home Messages Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 25 - Alphabet Soup | Overview of Myeloma Treatments 47:20

17 weeks yang lalu47:20

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RVd, KTd, CyBorD, DVd, EloRd - Looks like the cat got on the keyboard. Oh wait, this is just the myeloma regimens in day therapy today. Come on a journey as we attempt (mostly successfully) to avoid drug trade names! Let go of your proteasome inhibitions, phenotype your red cells and let us modulate your understanding of what it is to treat myeloma with an alphabet soups worth of drugs. We sincerely apologise to our endocrinology colleagues for how much dexamethasone we use in this episode but also generally. Timestamps 4:00 - Overview of the treatment journey 9:49 - Steroids - not the bulking kind 13:54 - Immunomodulators - the IMiDs 19:46 - Proteasome inhibitors - Bortezomib, Carflizomib 24:45 - Monoclonal antibodies - Daratumumab, Elotuzumab 28:31 - SINE Inhibitor - Selinexor 29:27 - Antibody-drug conjugates - Belantamab mafodotin 30:27 - CELMoDs - Iberdomide, mezigdomide 31:06 - Standard chemotherapy 33:15 - Autologous stem cell transplant 38:21 - T-cell directed therapy - BiTes, CAR-T 40:57 - Supportive care Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

Bloody Minded

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Episode 24 - Blue Fried Eggs | Intro to Multiple Myeloma 28:35

18 weeks yang lalu28:35

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== I do not like blue eggs and ham, I do not like them, Sam I Am. They crowd and clump, they grow too fast, Causing troubles that can last. They make my bones feel weak and sore, And through my kidneys they gnaw! I do not like blue eggs, you see, They're signs of something wrong with me. == Timestamps 3:35 - Recap of MGUS + smouldering myeloma 4:42 - Clinical case - Mr. Peter Rotein 8:15 - What is rouleaux? 10:30 - Bone marrow biopsies - what, how, how much ow? 15:29 - Multiple myeloma 16:41 - CRAB Criteria 18:26 - SLiM Criteria 19:24 - Clinical presentations of myeloma 21:48 - Plasmacytomas 22:56 - Causes of myeloma? 24:45 - Prognosis Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au…

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