Episode 6: Neurobiology of Pain - Exploring Neuropeptides with Dr. James Henry

Chronic Pain Chronicles with Dr Karmy

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In this episode, Dr Karmy is joined by Dr. James Henry, a pioneering expert in the field, where they dive deep into the neurobiology of pain.
Trained at McGill University and with a distinguished career spanning Western University and McMaster's Michael De Groote Pain Center, Dr. Henry brings a wealth of knowledge on the role of neuropeptides in chronic pain.
Join in on their conversation, as they explore how pain signals travel through the nervous system, the discovery and function of substance P, and the intricate interplay between the nervous and immune systems. They also discuss the challenges and limitations of translating animal model research to human chronic pain treatment.
This episode is a must-list for anyone interested in the cutting-edge science behind pain management.
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Chapter

1. Introduction (00:00:00)

2. Background of Pain Neurobiology (00:01:45)

3. Neuropeptide Substance P Discovery (00:08:12)

4. Development of Chronic Pain (00:14:40)

5. Significance of Substance P in Healing (00:16:41)

6. Immune System and Chronic Pain (00:21:26)

7. Potential of Substance P in Drug Development (00:22:28)

8. Chronic Pain in Animal Models (00:26:16)

9. Preventative Treatment from Dr. Henry's Patented Approaches (00:34:23)

10. Dr. Karmy's Concluding Thoughts (00:38:27)