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Konten disediakan oleh Dr Neil Love. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Dr Neil Love atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.
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HR-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Potential Role of PROTAC ER Degraders in Therapy for HR-Positive Metastatic Breast Cancer

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Manage episode 446868325 series 2530615
Konten disediakan oleh Dr Neil Love. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Dr Neil Love atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.

Featuring an interview with Dr Erika Hamilton, including the following topics:

  • Pathophysiology and pharmacology of ER-positive breast cancer treatment (0:00)
  • Clinical evidence available with oral selective estrogen receptor degraders (3:46)
  • Mechanism of action of proteolysis-targeting chimeras (PROTACs) (13:22)
  • PROTACs currently in clinical development (16:39)
  • Case: A woman in her late 30s with HR-positive, HER2-negative metastatic breast cancer (mBC) experiencing progression on a CDK4/6 inhibitor (CDK4/6i) and an aromatase inhibitor (AI) (35:09)
  • Case: A woman in her early 70s with HR-positive, HER2-negative mBC that progresses on a CDK4/6i and an AI (41:16)

CME information and select publications

  continue reading

1376 episode

Artwork
iconBagikan
 
Manage episode 446868325 series 2530615
Konten disediakan oleh Dr Neil Love. Semua konten podcast termasuk episode, grafik, dan deskripsi podcast diunggah dan disediakan langsung oleh Dr Neil Love atau mitra platform podcast mereka. Jika Anda yakin seseorang menggunakan karya berhak cipta Anda tanpa izin, Anda dapat mengikuti proses yang diuraikan di sini https://id.player.fm/legal.

Featuring an interview with Dr Erika Hamilton, including the following topics:

  • Pathophysiology and pharmacology of ER-positive breast cancer treatment (0:00)
  • Clinical evidence available with oral selective estrogen receptor degraders (3:46)
  • Mechanism of action of proteolysis-targeting chimeras (PROTACs) (13:22)
  • PROTACs currently in clinical development (16:39)
  • Case: A woman in her late 30s with HR-positive, HER2-negative metastatic breast cancer (mBC) experiencing progression on a CDK4/6 inhibitor (CDK4/6i) and an aromatase inhibitor (AI) (35:09)
  • Case: A woman in her early 70s with HR-positive, HER2-negative mBC that progresses on a CDK4/6i and an AI (41:16)

CME information and select publications

  continue reading

1376 episode

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