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Freely Filtered 054: EMPA Kidney!
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Manage episode 350708006 series 2540759
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Sophia Ambruso
Priya Yenebere
With Special Guest:
Brendon Neuen, Secretariat of the SGLT2 Trialists Consortium and cool guy on Twitter.
Editor:
Sophia Ambruso
Show Notes:
Joel’s Conflict of Interest Statement. Sophia is also conflicted with Astra Zeneca and Brendon with everybody in the SGLT2i space.
Joel starts off with a history of SGLT2i
EMPA-REG Outcomes. First!
CANVAS. OMG this signal is reproducible!
CREDENCE (🎧). It works in a dedicated population at high risk of kidney disease. And in a study designed for renal end-points.
DAPA-CKD (🎧). It’s not just for diabetics!
EMPA-Kidney. It works at really low GFR. And without albuminuria. And again in non-diabetics.
SGLT Inhibitors for Type 1 Diabetes: Proceed With Extreme Caution
Click to find the supplement (requires a subscription)
Differences in definition in the decreased renal function component of the composite primary outcomes.
EMPA-Kidney 40%
DAPA-Kidney 50%
CREDENCE doubling of serum Cr
Usability Testing of a Sick-Day Protocol in CKD (Pubmed)
New Guidelines for Statistical Reporting in the Journal (link, commentary on said guidelines by Frank Harrell)
The Peripheral on Amazon Prime
Unsealed the Tylenol Murders Podcast
Project Hail Mary by Andrew Weir
Lizzy McAlpine Singer Song Writer
Rachel Maddow Presents: Ultra
Twitter chaos continues. Get your Med-Mastodon handle
73 episode
Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on August 01, 2024 14:40 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 350708006 series 2540759
The Filtrate:
Joel Topf
Swapnil Hiremath
Josh Waitzman
Sophia Ambruso
Priya Yenebere
With Special Guest:
Brendon Neuen, Secretariat of the SGLT2 Trialists Consortium and cool guy on Twitter.
Editor:
Sophia Ambruso
Show Notes:
Joel’s Conflict of Interest Statement. Sophia is also conflicted with Astra Zeneca and Brendon with everybody in the SGLT2i space.
Joel starts off with a history of SGLT2i
EMPA-REG Outcomes. First!
CANVAS. OMG this signal is reproducible!
CREDENCE (🎧). It works in a dedicated population at high risk of kidney disease. And in a study designed for renal end-points.
DAPA-CKD (🎧). It’s not just for diabetics!
EMPA-Kidney. It works at really low GFR. And without albuminuria. And again in non-diabetics.
SGLT Inhibitors for Type 1 Diabetes: Proceed With Extreme Caution
Click to find the supplement (requires a subscription)
Differences in definition in the decreased renal function component of the composite primary outcomes.
EMPA-Kidney 40%
DAPA-Kidney 50%
CREDENCE doubling of serum Cr
Usability Testing of a Sick-Day Protocol in CKD (Pubmed)
New Guidelines for Statistical Reporting in the Journal (link, commentary on said guidelines by Frank Harrell)
The Peripheral on Amazon Prime
Unsealed the Tylenol Murders Podcast
Project Hail Mary by Andrew Weir
Lizzy McAlpine Singer Song Writer
Rachel Maddow Presents: Ultra
Twitter chaos continues. Get your Med-Mastodon handle
73 episode
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