#444 Macrocytosis, Hemolytic Anemia, Myelodysplastic Syndrome

The Curbsiders Internal Medicine Podcast

Recorded LIVE! At Johns Hopkins Internal Medicine Grand Rounds
Step up your anemia game as we explore the causes and diagnostic approach for macrocytic anemia, what to do with a reticulocyte count, the differential diagnosis for hemolytic anemia, the significance of the direct antiglobulin test, and diagnosis and management pearls for autoimmune hemolytic anemia (AIHA) and myelodysplastic syndrome (MDS). Plus, common questions and concerns regarding folate supplementation and the use of bone marrow biopsies. We’re joined by hematologist and pun enthusiast Dr. Rakhi Naik MD, MHS, @redcell_doc @hopkinsheme.
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Show Segments

• 00:00 Intro and Guest intro
• 05:53 Case 1: Elise - Macrocytic Anemia
• 14:59 Case 2: Jane - Hemolytic Anemia
• 23:24 Testing for Underlying Causes of Autoimmune Hemolytic Anemia
• 24:40 Association of Autoimmune Hemolytic Anemia with Lymphomas
• 25:10 Autoimmune Hemolytic Anemia: Diagnosis and Treatment
• 26:06 Management Approach for Autoimmune Hemolytic Anemia
• 27:30 Considerations for Outpatient Treatment of Autoimmune Hemolytic Anemia
• 28:18 Clotting Risk in Autoimmune Hemolytic Anemia
• 29:20 Treatment Options for Autoimmune Hemolytic Anemia
• 30:42 Long-Term Prognosis and Recurrence of Autoimmune Hemolytic Anemia
• 33:32 Diagnostic Challenges in Myelodysplastic Syndrome
• 35:00 Considerations for Folate Supplementation
• 36:24 Factors to Consider in the Management of Myelodysplastic Syndrome
• 39:30 When to Perform a Bone Marrow Biopsy in Myelodysplastic Syndrome
• 41:25 Shared Decision-Making in the Treatment of Myelodysplastic Syndrome

Credits

• Writer and Producer: Matthew Watto MD, FACP
• Show Notes: Matthew Watto MD, FACP
• Cover Art and Infographic: Matthew Watto MD, FACP
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Reviewer: Fatima Syed MD, MSc
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Rakhi P. Naik MD, MHS

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