Repairing Spinal Cord for a Wheelchair Free Future: Prof. Giuseppe Perale, Regenera

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We are speaking about the world where wheelchairs will not be needed after a spinal cord injury.
There are 250 000-500 000 spinal cord injuries globally each year.
“A bunch of crazy guys,” in the words of my guest, him included, wants the spinal cord to self-regenerate.
He is sure that in the future, we won’t be even speaking about regenerating the spinal cord after an accident
but about healing.
In this episode, you will hear

• how much time it takes from a spinal cord injury event, an accident, to reach an operating theatre – in Switzerland
• why this time is crucial
• how proprietary hydrogel and stem cells stop the cascade of events further damaging the spinal cord
• how mice after a spinal cord injury, could walk again
• and when will people after the spinal cord injury not need a wheelchair

Prof. Giuseppe Perale is the CEO of Regenera. A bioengineer who became hooked on regenerative medicine in high school and never let go. Apart from heading the neuroregeneration research lab at USI, Università della Svizzera italiana, he is also a motorcycle rider and a pilot.
Regenera is an Austrian-Swiss startup that aims to repair spinal cord injury in the subacute state. Their SpinoSave combines biomaterial – hydrogel and stem cells harvested from the patient’s fat tissue. The co-founders are Giuseppe Perale; Filippo Rossi, a chemical engineer; Pietro Rossi; Michael Raghunath, CMO.
Visit their website to stay up to date with progress in regenerating the spinal cord:
https://regenera.at/
Timestamps:
0:00 Prof. Giuseppe Perale and Regenera
1:10 Making Paralysis a Thing of the Past
3:17 What Causes Spinal Cord Injuries
5:44 What Is Paraplegia, What Is Tetraplegia
10:02 What Happens in the ER after a Spinal Cord Injury
17:56 Regenerative Medicine to Restore Damaged Tissue
26:59 Paraplegic Mice Could Walk Again, When Will People
35:35 Why Time Matters after a Spinal Cord Accident
39:21 Stopping the Cascade of Events in the Acute Spinal Cord Injury Phase to Induce Self-Regeneration
54:36 Preparing for Clinical Studies
56:55 Restoring Movement after Spinal Cord Injury in the Future
1:00:29 Thank You, Follow Regenera
1:01:25 Follow X-Health.show, Disclaimer
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The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.

Chapter

1. Prof. Giuseppe Perale and Regenera (00:00:00)

2. Making Paralysis a Thing of the Past (00:01:10)

3. What Causes Spinal Cord Injuries (00:03:17)

4. What Is Paraplegia, What Is Tetraplegia (00:05:44)

5. What Happens in the ER after a Spinal Cord Injury (00:10:02)

6. Regenerative Medicine to Restore Damaged Tissue (00:17:56)

7. Paraplegic Mice Could Walk Again, When Will People (00:26:59)

8. Why Time Matters after a Spinal Cord Accident (00:35:35)

9. Stopping the Cascade of Events in the Acute Spinal Cord Injury Phase to Induce Self-Regeneration (00:39:21)

10. Preparing for Clinical Studies (00:54:36)

11. Restoring Movement after Spinal Cord Injury in the Future (00:56:55)

12. Thank You, Follow Regenera (01:00:29)

13. Follow X-Health.show, Disclaimer (01:01:25)